Molecular classification of gastric cancer
نویسندگان
چکیده
منابع مشابه
Molecular Signaling in Tumorigenesis of Gastric Cancer
Gastric cancer (GC) is regarded as the fifth most common cancer and the third cause of cancer-related deaths worldwide. Mechanism of GC pathogenesis is still unclear and relies on multiple factors, including environmental and genetic characteristics. One of the most important environmental factors of GC occurrence is infection with Helicobacter pylori that is classified as class one carcinogens...
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Gastric cancer has a dismal prognosis and remains one of the deadly diseases worldwide. It has increasingly been recognized that gastric cancer is a heterogeneous disease, which may be subdivided into different groups based on histological, anatomical, and molecular classifications. New classifications combining histological features, anatomical locations, and molecular signatures will help imp...
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PURPOSE Gastric cancer may be subdivided into 3 distinct subtypes--proximal, diffuse, and distal gastric cancer--based on histopathologic and anatomic criteria. Each subtype is associated with unique epidemiology. Our aim is to test the hypothesis that these distinct gastric cancer subtypes may also be distinguished by gene expression analysis. EXPERIMENTAL DESIGN Patients with localized gast...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2016
ISSN: 0923-7534
DOI: 10.1093/annonc/mdw040